Glia, sympathetic activity and cardiovascular disease
نویسندگان
چکیده
منابع مشابه
Glia, sympathetic activity and cardiovascular disease
NEW FINDINGS What is the topic of this review? In this review, we discuss recent findings that provide a novel insight into the mechanisms that link glial cell function with the pathogenesis of cardiovascular disease, including systemic arterial hypertension and chronic heart failure. What advances does it highlight? We discuss how glial cells may influence central presympathetic circuits, lead...
متن کاملThe role of glia in neurological disease
Glial cells form a network in the central nervous system to support neurons and interact with them. The glia consist essentially of astrocytes that help with the nutrition of neurons and react in some cases of injury, oligodendrocytes that produce myelin, and microglia that are derived from the haemopoietic system and are concerned with the immunological defense of the nervous system. Experimen...
متن کاملThe role of glia in neurological disease
Glial cells form a network in the central nervous system to support neurons and interact with them. The glia consist essentially of astrocytes that help with the nutrition of neurons and react in some cases of injury, oligodendrocytes that produce myelin, and microglia that are derived from the haemopoietic system and are concerned with the immunological defense of the nervous system. Experimen...
متن کاملHIGHLIGHTED TOPIC Mechanisms of Sympathetic Regulation in Cardiovascular Disease Central neuromodulatory pathways regulating sympathetic activity in hypertension
Gabor A, Leenen FH. Central neuromodulatory pathways regulating sympathetic activity in hypertension. J Appl Physiol 113: 1294–1303, 2012. First published July 5, 2012; doi:10.1152/japplphysiol.00553.2012.—The classical neurotransmitters, glutamate and GABA, mediate fast (milliseconds) synaptic transmission and modulate its effectiveness through slow (seconds to minutes) signaling processes. An...
متن کاملPeripheral cardiac sympathetic hyperactivity in cardiovascular disease: role of neuropeptides.
High levels of sympathetic drive in several cardiovascular diseases including postmyocardial infarction, chronic congestive heart failure and hypertension are reinforced through dysregulation of afferent input and central integration of autonomic balance. However, recent evidence suggests that a significant component of sympathetic hyperactivity may also reside peripherally at the level of the ...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2016
ISSN: 0958-0670
DOI: 10.1113/ep085713